The draw for the Carabao Cup fourth round was conducted on Wednesday night.
Chelsea, who needed penalties to see off Aston Villa, will play Southampton next at Stamford Bridge.
Arsenal have been paired with Leeds, while Stoke will take on Brentford.
West Ham’s reward for eliminating Manchester United, is a tie against their rivals Manchester City.
Liverpool will face Preston in the next round.
Chelsea v Southampton
Arsenal v Leeds
Stoke v Brentford
West Ham v Man City
Leicester v Brighton
Burnley v Tottenham
QPR v Sunderland
Preston v Liverpool